When used together, these six SkinMedica® products have been clinically shown to reduce the appearance of hyperpigmentation as well as overall photodamage, while also helping to prevent their reoccurrence.
Appropriate for all skin types.
- Lytera® 2.0 Pigment Correcting Serum
- Total Defense + Repair Broad Spectrum Sunscreen SPF 34
- Retinol Complex 0.5
- AHA/BHA Exfoliating Cleanser
- AHA/BHA Cream
- Rejuvenative Moisturizer
Plus one free 1 oz. travel size Total Defense + Repair Broad Spectrum SPF 34 and SkinMedica® Travel Bag
*Save 20% when products are purchased as a kit.
Key Benefits of Lytera® 2.0 Advanced Pigment Correcting System
Proven to correct the appearance of hyperpigmentation and overall photodamage in a clinical study
Visible results seen as early as 4 weeks, with progressively dramatic improvements at weeks 8 and 12
Promotes a younger-looking, rejuvenated complexion
How to Use: AM / Morning
Moisten face with warm water and massage a small amount of SkinMedica® AHA/BHA Cleanser gently into skin using small circular motions. Rinse with lukewarm water and pat dry with a soft towel. Use daily as tolerated.
Apply a single pump of SkinMedica® Lytera® 2.0 Pigment Correcting Serum to face, neck, and chest or affected areas.
Apply a thin layer of SkinMedica® AHA/BHA Cream to your entire face.
Apply SkinMedica® Total Defense + Repair Sunscreen SPF 34 to your entire face. Reapply throughout the day as necessary.
How to Use: PM / Evening
Cleanse face with a mild cleanser, such as SkinMedica® Facial Cleanser. Rinse with lukewarm water and pat dry with a soft towel.
Apply a single pump of SkinMedica® Lytera® 2.0 Pigment Correcting Serum to face, neck, and chest or affected areas. Allow sufficient time for serum to dry before step 3.
Apply a single pump of SkinMedica® Retinol Complex 0.5 to face in the evening. If you have never used a Retinol product before, begin by limiting use to twice a week, gradually increasing frequency to every other night, and then advancing to each evening or as tolerated. Mild redness, peeling, and irritation is expected when using this product. Use daily sun protection with SPF 20 or higher during use of this product. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.
Apply SkinMedica® Rejuvenative Moisturizer to your entire face.
For All Products
Avoid getting in eyes. If contact occurs, rinse thoroughly with water.
The AHA/BHA Exfoliating Cleanser and AHA/BHA Cream in the Lytera® 2.0 Advanced Pigment Correcting System contains an alpha-hydroxy acid (AHA) that may increase your skin’s sensitivity to the sun an particularly the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using these products and for a week following.
Sunscreen is required to optimize and maintain the results of using the system.
Store at room temperature 15°c – 30°c (59°F – 86°F).
Do not use Retinol Complex if you are pregnant, lactating, or planning to become pregnant. Mild redness, peeling, and irritation may occur when using Retinol Complex.
What are the benefits of the Lytera® 2.0 Advanced Pigment Correcting System?
Lytera® 2.0 Advanced Pigment Correcting System is an all-in-one system for optimal skin evening, rejuvenation, and UV & infrared protection, which not only reduces the appearance of hyperpigmentation but also addresses overall photodamage.
What products are in the system?
There are 6 products included in the system: Lytera® 2.0 Pigment Correcting Serum, TOTAL DEFENSE + REPAIR Broad Spectrum SPF 34 Sunscreen, Retinol Complex 0.5, Rejuvenative Moisturizer, AHA/BHA Exfoliating Cleanser, and AHA/BHA Cream.
What does each individual product in the system do?
- Lytera® 2.0 Pigment Correcting Serum: Addresses the appearance of stubborn skin discoloration across diverse patient populations
- TOTAL DEFENSE + REPAIR Broad Spectrum SPF 34 Sunscreen: Defends against harmful UVA, UVB, and infrared rays while supporting the skin’s ability to restore itself
- AHA/BHA Exfoliating Cleanser: Gently scrubs away dead skin, promotes cellular turnover, and improves the appearance of skin texture and tone
- AHA/BHA Cream: Exfoliates and improves the appearance of skin tone and texture revealing brighter skin
- Rejuvenative Moisturizer: Helps nourish, hydrate, and rejuvenate skin
- Retinol Complex 0.5: Renews skin and diminishes the appearance of fine lines
What ingredient in the system helps improve the appearance of overall photodamage?
The proprietary blend of antioxidants in TOTAL DEFENSE + REPAIR Broad Spectrum SPF 34 Sunscreen, SOL-IR™ Advanced Antioxidant Complex, has been clinically proven to improve the appearance of photodamage while also promoting skin rejuvenation.
Can patients add other topical or prescription-strength products to this regimen?
Lytera® 2.0 Pigment Correcting Serum is developed to work as both monotherapy and in combination with other treatment plans for optimal results. However, it is at the physician’s discretion whether or not to supplement the system with additional products.
How does this system compare to prescription-strength systems on the market?
The Lytera® 2.0 Advanced Pigment Correcting System was clinically shown to deliver results comparable to a leading prescription-strength system on the market.
What skin type is appropriate for the Lytera® 2.0 Advanced Pigment Correcting System?
The system was very well tolerated in the clinical study across a wide range of ethnicities and skin types, with Fitzpatrick Skin Type III–V represented.
Can patients with sensitive skin use the Lytera® 2.0 Advanced Pigment Correcting System?
The system was very well tolerated in the clinical study across a wide range of ethnicities and skin types. However, as with all SkinMedica® products, we defer to our physician partners in recommending products that best suit their patients’ skin types.
What are common side effects?
During the clinical trials, no subjects reported adverse events. Mild peeling, redness, and irritation may occur when using Retinol Complex. Patients should be encouraged to consult with their healthcare provider if they are experiencing any side effects.
Can the system be used during pregnancy?
The system includes Retinol Complex. Patients should NOT use any retinol product if they are pregnant, lactating, or planning to become pregnant.
How long should the system last?
If used according to the directions, each system should last approximately 90 days.
How many steps are there in the treatment regimen?
There are 4 steps recommended in the morning and 4 steps in the evening.
How long should patients use the system?
Hyperpigmentation is a chronic condition and results may vary depending on severity of the condition. In a clinical efficacy and tolerability study, the Lytera® 2.0 Advanced Pigment Correcting System was studied over 12 weeks. Results were documented at weeks 4, 8, and 12. For optimal results and long-term maintenance, patients must adhere to the treatment plan, use sunscreen daily, and avoid excessive sun exposure.
What value does the system offer versus purchasing each product individually?
When purchasing the system, patients save over 20% as compared to purchasing all 6 products individually. In addition, they receive a free 1 oz. TOTAL DEFENSE + REPAIR Broad Spectrum SPF 34 Sunscreen, a premium SkinMedica® travel bag, and a $40 Brilliant Distinctions® rebate for their next system purchase.
CAUTION: Do not use Retinol Complex if you are pregnant, lactating, or planning to become pregnant. Mild redness, peeling, and irritation are expected when using these products. Use a sunscreen and limit sun exposure while using these products, and for a week following discontinuation.
CAUTION: GlyPro products used together may cause irritation.
Sunburn alert: AHA/BHA Exfoliating Cleanser, AHA/BHA Cream, and all GlyPro products contain an alpha-hydroxy acid (AHA) that may increase your skin’s sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using these products, and for a week following discontinuation.
IMPORTANT! SUNSCREEN IS REQUIRED TO OPTIMIZE AND MAINTAIN THE RESULTS OF USING LYTERA® 2.0 PIGMENT CORRECTING SERUM.
Most SkinMedica® products are intended to meet the FDA’s definition of a cosmetic product, an article applied to the human body to cleanse, beautify, promote attractiveness, and alter appearances. These SkinMedica® products are not intended to be drug products that diagnose, treat, cure, or prevent any disease or condition. These products have not been approved by the FDA, and the statements have not been evaluated by the FDA.
SkinMedica® TOTAL DEFENSE + REPAIR Broad Spectrum Sunscreens (SPF 34, SPF 34 Tinted, and SPF 50+) and Essential Defense Broad Spectrum Sunscreens (Everyday Clear SPF 47, Mineral Shield Tinted SPF 32, and Mineral Shield SPF 35) are over-the-counter drug products that are formulated and marketed pursuant to the FDA’s governing regulations set forth at 21 CFR Part 352.
The PA rating system is used in Japan to classify UVA protection and is not an FDA requirement on sunscreens sold in the U.S.
SkinMedica® Acne System, Acne Treatment Lotion, Purifying Foaming Wash, and Purifying Toner are over-the-counter drug products that are formulated and marketed pursuant to the FDA’s governing regulations set forth at 21 CFR Part 333 Subpart D.
Not all products are available in Canada. Subject to change at any time without prior notice.